Kathleen Sebelius has resigned after serving five years as secretary of the Department of Health and Human Services.
President Barack Obama is expected to nominate Sylvia Mathews Burwell, director of the Office of Management and Budget (OMB), to replace Sebelius, news organizations report.
The Senate will have to confirm Burwell, who was approved by a 96-0 vote to take the helm at OMB last year.
Should she be confirmed, Burwell will lead preparation for the next open-enrollment period for the nation’s health insurance exchanges and the delayed employer mandate, news reports say.
During her tenure at HHS, Sebelius made Medicare fraud prevention a priority. In 2009, Sebelius and Attorney General Eric Holder formed the Health Care Fraud Prevention and Enforcement Action Team (HEAT); and expanded the scope of Strike Force operations.
Sebelius’s tenure was marked by heavy criticism of her department’s messy rollout of the Affordable Care Act’s insurance marketplace exchanges.